2014.05 Nigel Cairns


On May 6, 2014, at the annual meeting of The CART Fund, Nigel J. Cairns, PhD, FRCPath, Professor, Department of Neurology, Washington University School of Medicine, St. Louis, MO was awarded a CART Grant in the amount of $250,000.

Research Project

Although we have learned a great deal about the biology of Alzheimer’s in recent years there is still no effective treatment. Dr. Cairns and colleagues plan to use the CART award to investigate a promising new molecule to see if it can slow down or stop the damage caused to nerve cells by the disease. Firstly, he plans to investigate how this new molecule works in the test tube and, secondly, he will investigate its effects in a mouse model of the human disease. If these approaches are successful he plans to move the lead molecule forward in the drug development pipeline towards clinical trials.