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Gabriela Chiosis | CART Fund 2016 Grant

Posted by on Apr 26, 2016 in News | 0 comments

Gabriela Chiosis | CART Fund 2016 Grant

The CART Fund is pleased to announce that Gabriela Chiosis, Ph.D., Memorial Sloan Kettering Cancer Center, has been selected to receive a 2016 Alzheimer’s research grant in the amount of $50,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC.

Research Project: A chemoproteomics approach to identify molecular changes in Alzheimer’s disease for therapy and diagnostic development

Current Alzheimer’s disease (AD) treatments only suppress symptoms as the disease continues to progress. For treatments that slow or reverse the disease, we must identify the proteins associated with AD progression before the neurons die. Attempts so far have been hindered by a lack of access to patient neurons in amounts sufficient for analyses and of sensitive techniques that inquire into biochemical changes that occur in neurons during disease initiation.

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Frank R. Sharp | CART Fund 2016 Grant

Posted by on Apr 21, 2016 in News | 0 comments

Frank R. Sharp | CART Fund 2016 Grant

The CART Fund is pleased to announce that Frank Sharp, M.D., University of California, Davis, has been selected to receive a 2016 Alzheimer’s research grant, in the amount of $125,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC.

Research Project: Discovery of Lipopolysaccharide in amyloid plaques and peri-vascular amyloid in brains with Alzheimer’s disease

How Alzheimer’s disease forms in the human brain is a complex process that, in some people, derives from vascular damage resulting from inadequate blood supply (ischemia) or stroke. But how does that damage turn into Alzheimer’s?

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Yueming Li | CART Fund 2016 Grant

Posted by on Apr 18, 2016 in News | 0 comments

Yueming Li | CART Fund 2016 Grant

The CART Fund is pleased to announce that Yueming Li, Ph.D., Memorial Sloan Kettering Cancer Center, has been selected to receive a 2016 Alzheimer’s research grant, in the amount of $250,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC.

Research Project: Identification of small molecules and therapeutic targets in autophagic pathways for Alzheimer’s disease

In 2002, Memorial Sloan Kettering Cancer Center (MSK) recruited Yueming Li from Merck Research, where he had been investigating the mechanism and therapeutics of Alzheimer’s disease (AD). As a biochemist, Dr. Li’s work at MSK uses chemical principles to develop less toxic, more effective treatment for cancers and AD, as well as other aging-related disorders.

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Chihiro Sato | CART Fund 2016 Grant

Posted by on Apr 18, 2016 in News | 0 comments

Chihiro Sato | CART Fund 2016 Grant

The CART Fund is pleased to announce that Chihiro Sato, Ph.D., Washington University in St. Louis School of Medicine, has been selected to receive a 2016 Alzheimer’s research grant, in the amount of $125,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC.

Research Project: Quantitative analysis of Tau in the Brain, CSF and cell models

The brains of people with Alzheimer’s disease (AD) are characterized by two abnormal structures: plaques, clusters of a protein fragment called beta amyloid which are found between brain cells; and tangles, knots of a protein called tau which are found inside brain cells. Tau is quite complex: there are several different versions of the protein, and it can be chemically modified (a process called phosphorylation) in several different

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