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Share CART at RI in Atlanta

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Share CART at RI in Atlanta

Are you attending the Rotary International Convention in Atlanta in June? Would you like to donate an hour to work the CART booth in the House of Friendship? This is your chance to share the story of CART with Rotarians from around the globe. If you are a Rotarian and would like to volunteer, click here. If you are a spouse or friend of a Rotarian and would like to volunteer, click here. Questions?  Contact Norman Rogers – 910-616-1205 or...

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Claudio Torres | CART Fund 2017 Grant

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Claudio Torres | CART Fund 2017 Grant

Research Project:  Neuron Senescence as Mediator of Neurodegeneration in Alzheimer’s disease The CART Fund will award Claudio Torres, Ph.D., Drexel University College of Medicine, a 2017 research grant in the amount of $50,000. The grant will be awarded on May 9, 2017 at the Annual Meeting of The CART Fund in Columbia, SC. Summary of Research Project: Alzheimer’s Disease (AD) currently affects about 5.4 million Americans and currently has no cure. Aging is the greatest risk factor for AD; however, the mechanisms of aging that predispose the brain to the development of the disease are still largely unknown. Cellular senescence is a hallmark of aging that may...

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Michael Karin | CART Fund 2017 Grant

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Michael Karin | CART Fund 2017 Grant

Research Project:   Inhibition of NLRP3 inflammasome activation – a new strategy for prevention and treatment of Alzheimer’s Disease and late onset neurodegeneration. The CART Fund will award Michael Karin Ph.D., University of California, San Diego School of Medicine, a 2017 research grant in the amount of $150,000. The grant will be awarded on May 16, 2017 at a meeting of The CART Fund in Orlando, FL. Summary of Research Project Alzheimer’s disease (AD) is the most common form of age-related dementia that exerts an incredible emotional and economic toll on our aging society. Currently, there are no effective treatments for AD or preventive measures that can...

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Tong Li | CART Fund 2017 Grant

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Tong Li | CART Fund 2017 Grant

Research Project:  Determining the contributions of age and neuroinflammation on the pathological conversion of tau The CART Fund will award Tong Li, Ph.D., Johns Hopkins University School of Medicine, a 2017 research grant in the amount of $75,000. The grant will be awarded on May 9, 2017 at the Annual meeting of The CART Fund in Columbia, SC. Alzheimer’s disease (AD), the most common form of dementia and a devastating illness for the elderly, is characterized by built-up of clumped proteins observed inside (called tau aggregates) and outside (called amyloid-beta (Aβ) plaques) of nerve cells that lead to memory problems and eventual loss of these cells. Past and...

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Tsuneya Ikezu | CART Fund 2017 Grant

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Tsuneya Ikezu | CART Fund 2017 Grant

Research Project: Therapeutic evaluation of novel tau kinase inhibitors in Alzheimer’s disease The CART Fund is pleased to announce that Tsuneya Ikezu, MD, Ph.D., Boston University School of Medicine, has been selected to receive a 2017 Alzheimer’s research grant in the amount of $100,000. The grant will be awarded on May 9, 2017 at the annual meeting of The Coins for Alzheimer’s Research Trust Fund (CART Fund) in Columbia, SC. Dr. Ikezu’s team is interested in the  development of small molecule drugs that would suppress the aggregation of tau protein in the brain, as the accumulation of this protein is believed to cause Alzheimer’s disease. The new compound,...

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Philip F. Copenhaver | CART Fund 2017 Grant

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Philip F. Copenhaver | CART Fund 2017 Grant

Research Project: A novel modulator of membrane estrogen receptors for treating AD Key Collaborator: Dr. Joseph Quinn, MD The CART Fund will award Philip Copenhaver, Ph.D., Oregon Health & Science University, a 2017 Alzheimer’s research grant in the amount of $75,000. The grant will be awarded on May 16, 2017 at a meeting of The CART Fund in Orlando, Florida. Alzheimer’s Disease (AD) involves the abnormal buildup of beta-amyloid and tau levels in the brain, but clinical trials designed to prevent their accumulation have been unsuccessful.   In contrast, a drug that could protect nerve cells against these toxic proteins might provide an alternative strategy for...

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