Posts by dytekllc

Live Smart

Posted

Live Smart

Read More

Dr. Kurt Brunden

Posted

Dr. Kurt Brunden

Research Associate Professor Scientific Director, Marian S. Ware Alzheimer and Benaroya Parkinson’s Disease Drug Discovery Programs Dr. Burnden’s proposal is close behind Puglieli’s in terms of proximity to animal model testing, after Brunden does some toxicology. Brudens proposal focuses on a family of aminothienopyridizine (ATPZs) compounds that emerged from 290,000 compound screens for drugs to block tangle formation in AD. He has identified several ATPZs that are worthy of bringing forward in animal studies.

Read More

MAYO JAX – Dr. Malcolm Leissering

Posted

MAYO JAX – Dr. Malcolm Leissering

The Leissering lab studies substances (called proteases) that destroy amyloid beta-protein which is the chief component of the plaques that create Alzheimer’s disease. Dr. Leissring previous work has shown that the severity of Alzheimer’s Disease is strongly dependent on how active these protease substances are. However, all of the various amyloid destroying substances (proteases) are not known. Dr. Leissring is using CART funds to investigate most of these substances and determine which ones are capable of destroying Alzheimer’s amyloids. The results are expected to give new insight into the causes of Alzheimer’s and perhaps help develop new...

Read More

2010 Grants

Posted

2010 Grants

Paul Murphy, University of Kentucky ($250,000 2yr. Grant)Alzheimer’s disease is sometimes called “the diabetes” of the brain, because, like diabetes, it is common and shares some common features including accumulation of proteinaceous deposits called amyloid. Moreover, until recently, it wasn’t apparent that diabetes itself is a risk factor for AD, and insulin, a key hormone regulating the body’s ability to respond to glucose (“sugar”) levels in the blood and centrally involved in the pathogenesis of diabetes, also has important effects on brain cells and the cellular and molecular processes involved in AD. Dr. Murphy’s...

Read More

Cleveland Clinic and University of Alabama Birmingham awarded 2008 CART grants

Posted

Cleveland Clinic and University of Alabama Birmingham awarded 2008 CART grants

For the first time in 2008, the CART Fund was able to make two grants in one year. From 56 outstanding applicants, our Scientific Review Committee chaired by Dr. John Trojanowski of the University of Pennsylvania, assisted by Dr. Allan Levey of Emory University and Dr. Karl Herrup of Rutgers University, recommended that our grants be made to Dr. Sanjay Pimplikar of the Cleveland Clinic ($250,000.00) and Dr. David Sweatt of UAB ($200,000.00). Dr. Pimplikar’s research will explore the possibility that an emyloid percusor protein, called AICD, is the real culprit in causing Alzheimer’s disease. Up to now most scientists have focused on the A-beta part of the...

Read More

Cart Fund presents 2007 grant to Mayo Clinic – Jacksonville

Posted

On May 2, 2007 at the annual meeting of the CART Board of Directors held in Columbia, SC, Dr. Todd Golde of the Mayo Clinic in Jacksonville, Florida was awarded the eighth CART Fund grant for research into Alzheimer’s Disease. Pictured left to right are PDG Jim Puryear – CART Vice President and CART Grants Chairman, Eric Puckett – CART Secretary, Karen Shore – CART President, PDG Bruce Baker – CART President Emeritus, Dr. Todd Golde – Mayo Clinic and Grant recipient, Roger Ackerman – CART Treasurer, and PDG Glenn Hood – CART Vice President This makes the total CART grants $1,850,000. Rotarians and others have now donated...

Read More

Cart Fund presents grant to University of Texas Medical Branch

Posted

On May 3, 2006 at the annual meeting of the CART Board of Directors held in Columbia, SC, Dr. Claudio Soto of the University of Texas Medical Branch was awarded the seventh CART Fund grant for research into Alzheimer’s Disease. Pictured left to right are CART Secretary PDG Dean Kanipe D-7670, Vice President Karen Shore D-7680, Dr. Soto, President Bruce Baker D-7750, Treasurer Roger Ackerman D-7770 and Vice President Jack Bass D-7770. This makes the total CART grants $1,600,000.

Read More

CART Fund Day proclaimed SC Governor proclaims ‘Carroll Campbell CART Fund Day’

Posted

WHEREAS, it is estimated that over 4 million people across the country suffer from Alzheimer’s disease, and medical scientists predict that, without a cure, one out of every ten living Americans will fall victim to this disease: and WHEREAS, initiated in 1995, The Rotary Coins for Alzheimer’s Research Trust Fund (CART) utilizes donated change as an effective means to raise funds for research into the prevention, early detection, and cure of Alzheimer’; and WHEREAS, over the past ten years, the CART fund has raised over $1,000,000 dollars and awarded $1,350,000 in grants for Alzheimer’s research; and WHEREAS, hosted by the Georgetown Rotary Club,...

Read More

CART announces 2005 research grant – Cart Fund presents grant to UCLA

Posted

In May of 2005, the sixth grant made by the CART Fund was presented to Dr. Gary Small and his research team from UCLA. They received a check for $250,000. UCLA was selected ahead of 70 other applicants from research centers in over 40 states. This makes the total CART grants $1,350,000.00. The UCL:A scientists are the first to develop technology that will provide a direct measure of plaque and tangle density in the living patient. The plaque and tangles are commonly found in all Alzheimer’s patients. Using only human volunteers, their project will be the first ever to detail the use of this technology in people at risk for Alzheimer’s. This research hopefully...

Read More

CART honored at symposium

Posted

On Friday, July 23 a delegation of six Rotarians from the Carolinas and Georgia plus four of their spouses attended a Symposium honoring The CART Fund in Philadelphia. The event was scheduled to follow the closing day of an International Conference on Alzheimer’s Research so that the scientists participating and/or attending could be present. “It was for me one of the most memorable events of my almost 38 years in Rotary,” said CART Treasurer Roger Ackerman. It was planned by and CO-chaired by Dr. John Trojanowski and Dr. Sam Gandy with assistance of four of CART’s grant recipients. The Symposium included research reports from eight of our...

Read More

CART announces 2004 research grant University of Connecticut Health Center receives $250,000 award

Posted

May 4, 2004 — At the annual meeting of the CART Board of Directors in Columbia, SC, the University of Connecticut Health Center was announced as the recipient of its fifth grant in the amount of $250,000.00 for research that will take place over the next two years. Dr. Robert Reenan, principal Investigator of this research, was on hand to receive the award and check. The University of Connecticut was the unanimous choice of the three scientists who reviewed all of the applications and reported their findings in a conference call with the CART Grants Committee chaired by Dr. Jack Bass of the Hilton Head Rotary Club. Initially their were 34 research centers who...

Read More

CART Named SC Angel Rotary program gives 99% of funds raised to research

Posted

November 19, 2003 — South Carolina Secretary of State Mark Hammond announced the 2003 Angels and Scrooges List at a news conference held at the State House Auditorium in Columbia. The annual designation of the best and worst charities as Angels or Scrooges has become a South Carolina tradition, receiving national recognition from news organizations, such as “Fleecing of America” on NBC Nightly News with Tom Brokaw. Secretary Hammond stated, “As your new Secretary of State, I am happy to continue this nationally recognized South Carolina tradition One of my duties as your Secretary of State is to guard the dollars you give to charity, and I want...

Read More