Posts by bivey

Yueming Li | CART Fund 2016 Grant

Yueming Li | CART Fund 2016 Grant

The CART Fund is pleased to announce that Yueming Li, Ph.D., Memorial Sloan Kettering Cancer Center, has been selected to receive a 2016 Alzheimer’s research grant, in the amount of $250,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC. Research Project: Identification of small molecules and therapeutic targets in autophagic pathways for Alzheimer’s disease In 2002, Memorial Sloan Kettering Cancer Center (MSK) recruited Yueming Li from Merck Research, where he had been investigating the mechanism and therapeutics of Alzheimer’s disease (AD). As a biochemist, Dr. Li’s work at MSK uses chemical...

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Chihiro Sato | CART Fund 2016 Grant

Chihiro Sato | CART Fund 2016 Grant

The CART Fund is pleased to announce that Chihiro Sato, Ph.D., Washington University in St. Louis School of Medicine, has been selected to receive a 2016 Alzheimer’s research grant, in the amount of $125,000. The grant will be awarded on May 3, 2016 at the annual meeting of The CART Fund in Columbia, SC. Research Project: Quantitative analysis of Tau in the Brain, CSF and cell models The brains of people with Alzheimer’s disease (AD) are characterized by two abnormal structures: plaques, clusters of a protein fragment called beta amyloid which are found between brain cells; and tangles, knots of a protein called tau which are found inside brain cells. Tau is...

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SC Governor Nikki Haley names 4/23/16 “Rotary CART Fund Day”

SC Governor Nikki Haley names 4/23/16 “Rotary CART Fund Day”

South Carolina Governor Nikki Haley has proclaimed April 23, 2016 as ”Rotary CART Fund Day”. This honor recognizes the $5.8 M of Alzheimer’s research grants awarded by The CART Fund. It also recognizes the 10th Annual Shag Festival to be hosted that day by the Rotary Club of Georgetown, SC which benefits The CART Fund. The CART Fund contributes to the prevention and cure of Alzheimer’s Disease through seed money Alzheimer’s research grants. One-hundred percent of every dollar donated to The CART Fund goes to Alzheimer’s research. The CART Fund is a 501(c)(3) organization.

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DIY Club CART Program (25 min.)

DIY Club CART Program (25 min.)

Whether Coins for Alzheimer’s Research Trust (CART) is new to your club, or a long-supported effort, here is a do-it-yourself, ready-to-go CART program. 1 ) Stream the made-for-TV episode: “Remembering No More” (22 minutes, free of commercial advertisements) 2 ) Q&A using Frequently Asked Questions about CART Join our efforts in the prevention and cure for Alzheimer’s disease. The CART Fund collects voluntarily contributions and makes periodic awards to qualified US institutions conducting research for the prevention and / or cure of Alzheimer’s disease. Each week at Rotary meetings, participating clubs and individual Rotarians donate...

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TV episode of Life in the Carolinas features CART

TV episode of Life in the Carolinas features CART

As The CART Fund celebrates is twentieth year it has been featured in a segment of Carl White’s Life in the Carolinas, “Remembering No More: A Story of Change – Life in the Carolinas Alzheimer’s Special”. This episode shines a spotlight on some of the unique aspects of The CART Fund.  Front and center is CART’s unique role in funding cutting-edge, innovative Alzheimer’s research projects.  This approach distinguishes CART from other funding sources that tend to favor established projects and labs. Featured in this episode is CART Founder Roger Ackerman.  Roger Ackerman encountered Alzheimer’s disease first hand during his...

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Beth Stevens named MacArthur Fellow

Beth Stevens named MacArthur Fellow

2013 CART grant recipient Beth Stevens, Ph.D. has been named a 2015 MacArthur Fellow by the MacArthur Foundation. Dr. Stevens is an Assistant Professor of Neurology, F. M. Kirby Neurobiology Center, Boston Children’s Hospital. The MacArthur Fellows Program awards unrestricted $625,000 fellowships to talented individuals who have shown extraordinary originality and dedication in their creative pursuits and a marked capacity for self-direction. Beth Stevens researches the “pruning” function of microglial cells or removal of synaptic cells during brain development . Stevens’s discoveries indicate that adult neural circuitry is determined not only by the nerve cells but...

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CART Grant Applications Accepted Through 12/1/15

CART Grant Applications Accepted Through 12/1/15

The CART Fund begins its 2016 Grant process by welcoming Letters-of-Intent (LOIs) for Alzheimer’s research projects within the United States. The CART Fund provides financial support for Alzheimer’s research projects that may yet be supported by extensive preliminary data, but have the potential to substantially advance biomedical research. LOIs that include sufficient detail to communicate the importance of the study as well as information on its feasibility are due by December 1, 2015. Final grant selection will made by April 1, 2016. Additional details and the 2016 grant application schedule can be found here.

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CD sales benefits The CART Fund

CD sales benefits The CART Fund

“Johnny Hilton 1978” is an eclectic Southern Country Rock CD recorded by CART Assistant Treasurer Johnny Hilton. This gem features all original tunes written by Johnny back in the 70’s when he performed music full time. This digitally re-mastered CD features melodies and lyrics rooted in the small towns and farm land of the rural south, blossoming in Columbia, SC. A must-have recording to complete every CART supporter’s music collection. Proceeds from the sale of this CD will be donated to the CART fund for Alzheimer’s research. Get your copy today at www.johnnyhilton.com

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Ikezu Findings Prove Microglia Plays Crucial Role in Early Progression of Alzheimer’s Disease

Ikezu Findings Prove Microglia Plays Crucial Role in Early Progression of Alzheimer’s Disease

Video Summary Available Dr. Tsuneya Ikezu, MD, PhD, and colleagues from Boston University School of Medicine identify the role of Microglia in early AD progression in “Depletion of microglia and inhibition of exosome synthesis halt tau propagation” published in Nature Neuroscience on October 5, 2015. For the first time, researchers have determined how toxic tau fibrils spread by the help of brain immune cells called microglia during the early stages of Alzheimer’s disease (AD). The gradual decline in cognitive function and loss of neurons in patients with AD is preceded by the harmful build-up of the protein tau in the brain. Tau accumulates as tiny fibers called...

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McCrory honors NC Rotarians for Centennial and CART Support

McCrory honors NC Rotarians for Centennial and CART Support

North Carolina Governor Pat McCrory proclaimed the month of June 2015 as the “Rotary Club 100th Anniversary” month, to recognize the centennial of many Rotary clubs in the state. Governor McCrory’s proclamation specified that support of Coins for Alzheimer’s Research Trust (CART) would be the primary way that NC Rotarians would celebrate this important occasion. All six of the Rotary Districts in North Carolina support The CART Fund. Many thanks to the Rotarians in Districts 7670, 7680, 7690, 7710, 7720 and 7730. The CART Fund contributes to the prevention and cure of Alzheimer’s Disease through seed money Alzheimer’s research grants. One-hundred percent of every dollar...

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Koronyo-Hamaoui study named August ’Editor’s Choice’ in Brain

Koronyo-Hamaoui study named August ’Editor’s Choice’ in Brain

Research update from Dr. Maya Koronyo-Hamaoui, 2012 CART Grant Recipient: A paper published by Dr. Maya Koronyo-Hamaoui and colleagues from the department of Neurosurgery, Maxine-Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, Los Angeles, CA is named the “Editor’s Choice” for August 2015 in the Oxford University journal Brain. This large, multi-year study shows for the first time that that infiltrating monocyte-derived macrophages contribute to the clearance of amyloid-beta in the brain. Koronyo et al. show that monthly injection of a subset of bone marrow monocytes into the peripheral blood of symptomatic Alzheimer’s disease mouse models, and/or weekly...

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Erik Musiek, Washington University in St. Louis ($250,000 Grant)

Erik Musiek, Washington University in St. Louis ($250,000 Grant)

    On May 5, 2015, at the annual meeting of The CART Fund, Erik Musiek, MD, PhD., Washington University in St. Louis School of Medicine was awarded a CART Grant in the amount of $250,000. Research Project Dr. Musiek’s research is focused on understanding links between brain aging and Alzheimer’s disease. The goal of his work is to identify age-related processes in the brain that set the stage for Alzheimer’s disease, with the hope of developing therapies to prevent this process. One hallmark of aging is the decline of circadian rhythms, the 24-hour cycles which keep our body and cells coordinated with nature’s light-dark cycle. In Alzheimer’s disease, these...

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